Endorsed Study

Criteria for Selection

• Must be in collaboration with a TGN Core or TGN Academic Affiliate site
• The primary objective of each study must be to help move a geroscience-guided intervention from the bench to human studies and ultimately clinical care
• One or more biological hallmarks are targeted
• Pre-clinical evidence exists in animal models supporting its ability to target hallmarks
• Study design is guided by geroscience principles
• Outcomes include some combination of geroscience-relevant biomarkers, functional measures and/or chronic disease diagnoses
• Funding for the core study has either been obtained or plans for grant submission clearly described
• Sufficient institutional infrastructure
• Proposed study focus is well-aligned with TGN mission and will help ensure a well-balanced portfolio of TGN-sponsored studies
• Only US-based institutions eligible

Benefits of becoming a TGN Endorsed Study

• Access to background information pertaining to geroscience-guided approaches to study design, clinical outcomes and biomarkers – beyond to what is posted on the website
• Consultation hours with content experts (limited free assistance followed by cost recovery)   
• Assistance with TGN-related budgeting issues
• Eligible to participate in future data pooling analyses and projects

Expectations of a TGN Endorsed Study

• Willingness to seek funding for these studies if not already funded
• Must include TGN Core Service fees in grant applications
• Adherence to TGN policies as regards selection of outcome measures, use of standardized biomarker panels, SOPs, MOPs, and Biobanking protocols
• Agree single IRB if appropriate
• Willingness to share data and samples with other TGN sites/studies once appropriate IRB and privacy requirements are fulfilled.
• Cite TGN in all relevant publications if used TGN services (FGA, consultant hours)
• Sign a Letter of Understanding

If you have questions, please contact us.